Gene Family: Immunoglobulin heavy locus at 14q32.33 (IGH)
A subset of
:
Immunoglobulin heavy
IGH locus: The IGH locus is at 14q32.33 and contains IGHV (variable) genes, IGHD (diversity) genes, IGHJ (joining) genes, and IGHA, IGHG, IGHD, IGHE and IGHM constant genes. [Source: HGNC]
Genes contained within the family: 187
| Approved Symbol | Approved Name | Previous Symbols | Synonyms | Chromosome |
|---|---|---|---|---|
| IGH | immunoglobulin heavy locus | IGHDY1, IGH@ | 14q32.33 | |
| IGHV1-2 | immunoglobulin heavy variable 1-2 | V35 | 14q32.33 | |
| IGHV1-3 | immunoglobulin heavy variable 1-3 | VI-3B | 14q32.33 | |
| IGHV1-12 | immunoglobulin heavy variable 1-12 (pseudogene) | 14q32.33 | ||
| IGHV1-8 | immunoglobulin heavy variable 1-8 | 14q32.33 not on reference assembly | ||
| IGHV1-14 | immunoglobulin heavy variable 1-14 (pseudogene) | 14q32.33 | ||
| IGHV1-17 | immunoglobulin heavy variable 1-17 (pseudogene) | 14q32.33 | ||
| IGHV1-18 | immunoglobulin heavy variable 1-18 | 14q32.33 | ||
| IGHV1-24 | immunoglobulin heavy variable 1-24 | 14q32.33 | ||
| IGHV1-45 | immunoglobulin heavy variable 1-45 | 14q32.33 | ||
| IGHV1-46 | immunoglobulin heavy variable 1-46 | 14q32.33 | ||
| IGHV1-58 | immunoglobulin heavy variable 1-58 | 14q32.33 | ||
| IGHV1-67 | immunoglobulin heavy variable 1-67 (pseudogene) | 14q32.33 | ||
| IGHV1-68 | immunoglobulin heavy variable 1-68 (pseudogene) | 14q32.33 | ||
| IGHV1-69 | immunoglobulin heavy variable 1-69 | IGHV1-E | 14q32.33 | |
| IGHV1-69D | immunoglobulin heavy variable 1-69D | 14q32.33 | ||
| IGHV1-38-4 | immunoglobulin heavy variable 1-38-4 (non-functional) | IGHV1-C | IGHV1-c | 14q32.33 not on reference assembly |
| IGHV1-69-2 | immunoglobulin heavy variable 1-69-2 | IGHV1-F | IGHV1-f | 14q32.33 |
| IGHV2-5 | immunoglobulin heavy variable 2-5 | 14q32.33 | ||
| IGHV2-10 | immunoglobulin heavy variable 2-10 (pseudogene) | 14q32.33 not on reference assembly | ||
| IGHV2-26 | immunoglobulin heavy variable 2-26 | 14q32.33 | ||
| IGHV2-70 | immunoglobulin heavy variable 2-70 | 14q32.33 | ||
| IGHV2-70D | immunoglobulin heavy variable 2-70D | 14q32.33 | ||
| IGHV3-6 | immunoglobulin heavy variable 3-6 (pseudogene) | 14q32.33 | ||
| IGHV3-7 | immunoglobulin heavy variable 3-7 | 14q32.33 | ||
| IGHV3-9 | immunoglobulin heavy variable 3-9 | 14q32.33 | ||
| IGHV3-11 | immunoglobulin heavy variable 3-11 (gene/pseudogene) | 14q32.33 | ||
| IGHV3-13 | immunoglobulin heavy variable 3-13 | 14q32.33 | ||
| IGHV3-15 | immunoglobulin heavy variable 3-15 | 14q32.33 | ||
| IGHV3-16 | immunoglobulin heavy variable 3-16 (non-functional) | 14q32.33 | ||
| IGHV3-19 | immunoglobulin heavy variable 3-19 (pseudogene) | 14q32.33 | ||
| IGHV3-20 | immunoglobulin heavy variable 3-20 | 14q32.33 | ||
| IGHV3-21 | immunoglobulin heavy variable 3-21 | 14q32.33 | ||
| IGHV3-22 | immunoglobulin heavy variable 3-22 (pseudogene) | 14q32.33 | ||
| IGHV3-23 | immunoglobulin heavy variable 3-23 | 14q32.33 | ||
| IGHV3-25 | immunoglobulin heavy variable 3-25 (pseudogene) | 14q32.33 | ||
| IGHV3-29 | immunoglobulin heavy variable 3-29 (pseudogene) | 14q32.33 | ||
| IGHV3-30 | immunoglobulin heavy variable 3-30 | 14q32.33 | ||
| IGHV3-30-2 | immunoglobulin heavy variable 3-30-2 (pseudogene) | 14q32.33 | ||
| IGHV3-30-3 | immunoglobulin heavy variable 3-30-3 | 14q32.33 not on reference assembly | ||
| IGHV3-30-5 | immunoglobulin heavy variable 3-30-5 | 14q32.33 not on reference assembly | ||
| IGHV3-32 | immunoglobulin heavy variable 3-32 (pseudogene) | 14q32.33 | ||
| IGHV3-33 | immunoglobulin heavy variable 3-33 | 14q32.33 | ||
| IGHV3-33-2 | immunoglobulin heavy variable 3-33-2 (pseudogene) | 14q32.33 | ||
| IGHV3-35 | immunoglobulin heavy variable 3-35 (non-functional) | 14q32.33 | ||
| IGHV3-36 | immunoglobulin heavy variable 3-36 (pseudogene) | 14q32.33 | ||
| IGHV3-37 | immunoglobulin heavy variable 3-37 (pseudogene) | 14q32.33 | ||
| IGHV3-38 | immunoglobulin heavy variable 3-38 (non-functional) | 14q32.33 | ||
| IGHV3-41 | immunoglobulin heavy variable 3-41 (pseudogene) | 14q32.33 | ||
| IGHV3-42 | immunoglobulin heavy variable 3-42 (pseudogene) | 14q32.33 | ||
| IGHV3-43 | immunoglobulin heavy variable 3-43 | 14q32.33 | ||
| IGHV3-43D | immunoglobulin heavy variable 3-43D | 14q32.33 not on reference assembly | ||
| IGHV3-47 | immunoglobulin heavy variable 3-47 (pseudogene) | 14q32.33 | ||
| IGHV3-48 | immunoglobulin heavy variable 3-48 | 14q32.33 | ||
| IGHV3-49 | immunoglobulin heavy variable 3-49 | 14q32.33 | ||
| IGHV3-50 | immunoglobulin heavy variable 3-50 (pseudogene) | 14q32.33 | ||
| IGHV3-52 | immunoglobulin heavy variable 3-52 (pseudogene) | 14q32.33 | ||
| IGHV3-53 | immunoglobulin heavy variable 3-53 | 14q32.33 | ||
| IGHV3-54 | immunoglobulin heavy variable 3-54 (pseudogene) | 14q32.33 | ||
| IGHV3-57 | immunoglobulin heavy variable 3-57 (pseudogene) | 14q32.33 | ||
| IGHV3-60 | immunoglobulin heavy variable 3-60 (pseudogene) | 14q32.33 | ||
| IGHV3-62 | immunoglobulin heavy variable 3-62 (pseudogene) | 14q32.33 | ||
| IGHV3-63 | immunoglobulin heavy variable 3-63 (pseudogene) | 14q32.33 | ||
| IGHV3-64 | immunoglobulin heavy variable 3-64 | 14q32.33 | ||
| IGHV3-65 | immunoglobulin heavy variable 3-65 (pseudogene) | 14q32.33 | ||
| IGHV3-66 | immunoglobulin heavy variable 3-66 | 14q32.33 | ||
| IGHV3-71 | immunoglobulin heavy variable 3-71 (pseudogene) | IGHV3-G | IGHV3-g | 14q32.33 |
| IGHV3-72 | immunoglobulin heavy variable 3-72 | 14q32.33 | ||
| IGHV3-73 | immunoglobulin heavy variable 3-73 | 14q32.33 | ||
| IGHV3-74 | immunoglobulin heavy variable 3-74 | 14q32.33 | ||
| IGHV3-75 | immunoglobulin heavy variable 3-75 (pseudogene) | 14q32.33 | ||
| IGHV3-76 | immunoglobulin heavy variable 3-76 (pseudogene) | 14q32.33 | ||
| IGHV3-79 | immunoglobulin heavy variable 3-79 (pseudogene) | 14q32.33 | ||
| IGHV3-38-3 | immunoglobulin heavy variable 3-38-3 (non-functional) | IGHV3-D | IGHV3-d | 14q32.33 not on reference assembly |
| IGHV3-69-1 | immunoglobulin heavy variable 3-69-1 (pseudogene) | IGHV3-H | IGHV3-h | 14q32.33 |
| IGHV4-4 | immunoglobulin heavy variable 4-4 | 14q32.33 | ||
| IGHV4-28 | immunoglobulin heavy variable 4-28 | 14q32.33 | ||
| IGHV4-30-1 | immunoglobulin heavy variable 4-30-1 | 14q32.33 | ||
| IGHV4-30-2 | immunoglobulin heavy variable 4-30-2 | IGHV4-3, IGHV4302 | 14q32.33 | |
| IGHV4-30-4 | immunoglobulin heavy variable 4-30-4 | IGHV4-3, IGHV4304 | 14q32.33 not on reference assembly | |
| IGHV4-31 | immunoglobulin heavy variable 4-31 | 14q32.33 not on reference assembly | ||
| IGHV4-34 | immunoglobulin heavy variable 4-34 | 14q32.33 | ||
| IGHV4-39 | immunoglobulin heavy variable 4-39 | 14q32.33 | ||
| IGHV4-55 | immunoglobulin heavy variable 4-55 (pseudogene) | 14q32.33 | ||
| IGHV4-59 | immunoglobulin heavy variable 4-59 | 14q32.33 | ||
| IGHV4-61 | immunoglobulin heavy variable 4-61 | 14q32.33 | ||
| IGHV4-80 | immunoglobulin heavy variable 4-80 (pseudogene) | 14q32.33 | ||
| IGHV4-38-2 | immunoglobulin heavy variable 4-38-2 | IGHV4-B | 14q32.33 not on reference assembly | |
| IGHV5-51 | immunoglobulin heavy variable 5-51 | 14q32.33 | ||
| IGHV5-78 | immunoglobulin heavy variable 5-78 (pseudogene) | 14q32.33 | ||
| IGHV5-10-1 | immunoglobulin heavy variable 5-10-1 | IGHV5-A | IGHV5-a | 14q32.33 |
| IGHV6-1 | immunoglobulin heavy variable 6-1 | 14q32.33 | ||
| IGHV7-4-1 | immunoglobulin heavy variable 7-4-1 | 14q32.33 | ||
| IGHV7-40 | immunoglobulin heavy variable 7-40 (pseudogene) | 14q32.33 | ||
| IGHV7-27 | immunoglobulin heavy variable 7-27 (pseudogene) | 14q32.33 | ||
| IGHV7-56 | immunoglobulin heavy variable 7-56 (pseudogene) | 14q32.33 | ||
| IGHV7-34-1 | immunoglobulin heavy variable 7-34-1 (pseudogene) | 14q32.33 | ||
| IGHV7-81 | immunoglobulin heavy variable 7-81 (non-functional) | 14q32.33 | ||
| IGHVII-1-1 | immunoglobulin heavy variable (II)-1-1 (pseudogene) | IGHV(II)-1-1 | 14q32.33 | |
| IGHVII-15-1 | immunoglobulin heavy variable (II)-15-1 (pseudogene) | IGHV(II)-15-1 | 14q32.33 | |
| IGHVII-20-1 | immunoglobulin heavy variable (II)-20-1 (pseudogene) | IGHV(II)-20-1 | 14q32.33 | |
| IGHVII-22-1 | immunoglobulin heavy variable (II)-22-1 (pseudogene) | IGHV(II)-22-1 | 14q32.33 | |
| IGHVII-26-2 | immunoglobulin heavy variable (II)-26-2 (pseudogene) | IGHV(II)-26-2 | 14q32.33 | |
| IGHVII-28-1 | immunoglobulin heavy variable (II)-28-1 (pseudogene) | IGHV(II)-28-1 | 14q32.33 | |
| IGHVII-30-1 | immunoglobulin heavy variable (II)-30-1 (pseudogene) | IGHV(II)-30-1 | 14q32.33 | |
| IGHVII-30-21 | immunoglobulin heavy variable (II)-30-21 (pseudogene) | IGHV(II)-30-21 | 14q32.33 | |
| IGHVII-31-1 | immunoglobulin heavy variable (II)-31-1 (pseudogene) | IGHV(II)-31-1 | 14q32.33 not on reference assembly | |
| IGHVII-33-1 | immunoglobulin heavy variable (II)-33-1 (pseudogene) | IGHV(II)-33-1 | 14q32.33 | |
| IGHVII-40-1 | immunoglobulin heavy variable (II)-40-1 (pseudogene) | IGHV(II)-40-1 | 14q32.33 | |
| IGHVII-43-1 | immunoglobulin heavy variable (II)-43-1 (pseudogene) | IGHV(II)-43-1 | 14q32.33 | |
| IGHVII-44-2 | immunoglobulin heavy variable (II)-44-2 (pseudogene) | IGHV(II)-44-2 | 14q32.33 | |
| IGHVII-46-1 | immunoglobulin heavy variable (II)-46-1 (pseudogene) | IGHV(II)-46-1 | 14q32.33 | |
| IGHVII-49-1 | immunoglobulin heavy variable (II)-49-1 (pseudogene) | IGHV(II)-49-1 | 14q32.33 | |
| IGHVII-51-2 | immunoglobulin heavy variable (II)-51-2 (pseudogene) | IGHV(II)-51-2 | 14q32.33 | |
| IGHVII-53-1 | immunoglobulin heavy variable (II)-53-1 (pseudogene) | IGHV(II)-53-1 | 14q32.33 | |
| IGHVII-60-1 | immunoglobulin heavy variable (II)-60-1 (pseudogene) | IGHV(II)-60-1 | 14q32.33 | |
| IGHVII-62-1 | immunoglobulin heavy variable (II)-62-1 (pseudogene) | IGHV(II)-62-1 | 14q32.33 | |
| IGHVII-65-1 | immunoglobulin heavy variable (II)-65-1 (pseudogene) | IGHV(II)-65-1 | 14q32.33 | |
| IGHVII-67-1 | immunoglobulin heavy variable (II)-67-1 (pseudogene) | IGHV(II)-67-1 | 14q32.33 | |
| IGHVII-74-1 | immunoglobulin heavy variable (II)-74-1 (pseudogene) | IGHV(II)-74-1 | 14q32.33 | |
| IGHVII-78-1 | immunoglobulin heavy variable (II)-78-1 (pseudogene) | IGHV(II)-78-1 | 14q32.33 | |
| IGHVIII-2-1 | immunoglobulin heavy variable (III)-2-1 (pseudogene) | IGHV(III)-2-1 | 14q32.33 | |
| IGHVIII-5-1 | immunoglobulin heavy variable (III)-5-1 (pseudogene) | IGHV(III)-5-1 | 14q32.33 | |
| IGHVIII-5-2 | immunoglobulin heavy variable (III)-5-2 (pseudogene) | IGHV(III)-5-2 | 14q32.33 | |
| IGHVIII-11-1 | immunoglobulin heavy variable (III)-11-1 (pseudogene) | IGHV(III)-11-1 | 14q32.33 | |
| IGHVIII-13-1 | immunoglobulin heavy variable (III)-13-1 (pseudogene) | IGHV(III)-13-1 | 14q32.33 | |
| IGHVIII-16-1 | immunoglobulin heavy variable (III)-16-1 (pseudogene) | IGHV(III)-16-1 | 14q32.33 | |
| IGHVIII-22-2 | immunoglobulin heavy variable (III)-22-2 (pseudogene) | IGHV(III)-22-2 | 14q32.33 | |
| IGHVIII-25-1 | immunoglobulin heavy variable (III)-25-1 (pseudogene) | IGHV(III)-25-1 | 14q32.33 | |
| IGHVIII-26-1 | immunoglobulin heavy variable (III)-26-1 (pseudogene) | IGHV(III)-26-1 | 14q32.33 | |
| IGHVIII-38-1 | immunoglobulin heavy variable (III)-38-1 (pseudogene) | IGHV(III)-38-1 | 14q32.33 | |
| IGHVIII-44 | immunoglobulin heavy variable (III)-44 (pseudogene) | IGHV(III)-44 | 14q32.33 | |
| IGHVIII-47-1 | immunoglobulin heavy variable (III)-47-1 (pseudogene) | IGHV(III)-47-1 | 14q32.33 | |
| IGHVIII-51-1 | immunoglobulin heavy variable (III)-51-1 (pseudogene) | IGHV(III)-51-1 | 14q32.33 | |
| IGHVIII-67-2 | immunoglobulin heavy variable (III)-67-2 (pseudogene) | IGHV(III)-67-2 | 14q32.33 | |
| IGHVIII-67-3 | immunoglobulin heavy variable (III)-67-3 (pseudogene) | IGHV(III)-67-3 | 14q32.33 | |
| IGHVIII-67-4 | immunoglobulin heavy variable (III)-67-4 (pseudogene) | IGHV(III)-67-4 | 14q32.33 | |
| IGHVIII-76-1 | immunoglobulin heavy variable (III)-76-1 (pseudogene) | IGHV(III)-76-1 | 14q32.33 | |
| IGHVIII-82 | immunoglobulin heavy variable (III)-82 (pseudogene) | IGHV(III)-82 | 14q32.33 | |
| IGHVIV-44-1 | immunoglobulin heavy variable (IV)-44-1 (pseudogene) | IGHV(IV)-44-1 | 14q32.33 | |
| IGHD1-1 | immunoglobulin heavy diversity 1-1 | IGHD11 | 14q32.33 | |
| IGHD1-7 | immunoglobulin heavy diversity 1-7 | DM1, IGHD17 | 14q32.33 | |
| IGHD1-14 | immunoglobulin heavy diversity 1-14 (non-functional) | IGHD114, DM2 | 14q32.33 | |
| IGHD1-20 | immunoglobulin heavy diversity 1-20 | IGHD120 | 14q32.33 | |
| IGHD1-26 | immunoglobulin heavy diversity 1-26 | IGHD126 | 14q32.33 | |
| IGHD2-2 | immunoglobulin heavy diversity 2-2 | IGHD22 | 14q32.33 | |
| IGHD2-8 | immunoglobulin heavy diversity 2-8 | IGHD28, DLR1 | 14q32.33 | |
| IGHD2-15 | immunoglobulin heavy diversity 2-15 | IGHD215, D2 | 14q32.33 | |
| IGHD2-21 | immunoglobulin heavy diversity 2-21 | IGHD221 | 14q32.33 | |
| IGHD3-3 | immunoglobulin heavy diversity 3-3 | IGHD33, DXP4 | 14q32.33 | |
| IGHD3-9 | immunoglobulin heavy diversity 3-9 | IGHD39, DXP1 | 14q32.33 | |
| IGHD3-10 | immunoglobulin heavy diversity 3-10 | IGHD310, DXP'1 | 14q32.33 | |
| IGHD3-16 | immunoglobulin heavy diversity 3-16 | IGHD316 | 14q32.33 | |
| IGHD3-22 | immunoglobulin heavy diversity 3-22 | IGHD322 | 14q32.33 | |
| IGHD4-4 | immunoglobulin heavy diversity 4-4 | IGHD44, DA4 | 14q32.33 | |
| IGHD4-11 | immunoglobulin heavy diversity 4-11 (non-functional) | IGHD411, DA1 | 14q32.33 | |
| IGHD4-17 | immunoglobulin heavy diversity 4-17 | IGHD417 | 14q32.33 | |
| IGHD4-23 | immunoglobulin heavy diversity 4-23 (non-functional) | IGHD423 | 14q32.33 | |
| IGHD5-5 | immunoglobulin heavy diversity 5-5 | IGHD55, DK4 | 14q32.33 | |
| IGHD5-12 | immunoglobulin heavy diversity 5-12 | IGHD512, DK1 | 14q32.33 | |
| IGHD5-18 | immunoglobulin heavy diversity 5-18 | IGHD518 | 14q32.33 | |
| IGHD5-24 | immunoglobulin heavy diversity 5-24 (non-functional) | IGHD524 | 14q32.33 | |
| IGHD6-6 | immunoglobulin heavy diversity 6-6 | IGHD66, D(N4) | 14q32.33 | |
| IGHD6-13 | immunoglobulin heavy diversity 6-13 | IGHD613, DN1 | 14q32.33 | |
| IGHD6-19 | immunoglobulin heavy diversity 6-19 | IGHD619 | 14q32.33 | |
| IGHD6-25 | immunoglobulin heavy diversity 6-25 | IGHD625 | 14q32.33 | |
| IGHD7-27 | immunoglobulin heavy diversity 7-27 | IGHD727, DHQ52 | 14q32.33 | |
| IGHJ1 | immunoglobulin heavy joining 1 | 14q32.33 | ||
| IGHJ1P | immunoglobulin heavy joining 1P (pseudogene) | Jpsi1 | 14q32.33 | |
| IGHJ2 | immunoglobulin heavy joining 2 | 14q32.33 | ||
| IGHJ2P | immunoglobulin heavy joining 2P (pseudogene) | Jpsi2 | 14q32.33 | |
| IGHJ3 | immunoglobulin heavy joining 3 | 14q32.33 | ||
| IGHJ3P | immunoglobulin heavy joining 3P (pseudogene) | Jpsi3 | 14q32.33 | |
| IGHJ4 | immunoglobulin heavy joining 4 | 14q32.33 | ||
| IGHJ5 | immunoglobulin heavy joining 5 | 14q32.33 | ||
| IGHJ6 | immunoglobulin heavy joining 6 | 14q32.33 | ||
| IGHA1 | immunoglobulin heavy constant alpha 1 | 14q32.33 | ||
| IGHA2 | immunoglobulin heavy constant alpha 2 (A2m marker) | 14q32.33 | ||
| IGHG1 | immunoglobulin heavy constant gamma 1 (G1m marker) | 14q32.33 | ||
| IGHG2 | immunoglobulin heavy constant gamma 2 (G2m marker) | 14q32.33 | ||
| IGHG3 | immunoglobulin heavy constant gamma 3 (G3m marker) | 14q32.33 | ||
| IGHG4 | immunoglobulin heavy constant gamma 4 (G4m marker) | 14q32.33 | ||
| IGHGP | immunoglobulin heavy constant gamma P (non-functional) | IGHGP1 | 14q32.33 | |
| IGHD | immunoglobulin heavy constant delta | FLJ00382, FLJ46727, MGC29633 | 14q32.33 | |
| IGHE | immunoglobulin heavy constant epsilon | 14q32.33 | ||
| IGHEP1 | immunoglobulin heavy constant epsilon P1 (pseudogene) | 14q32.33 | ||
| IGHM | immunoglobulin heavy constant mu | 14q32.33 |
For further reading, please see: Lefranc M.-P. and Lefranc G. The Immunoglobulin FactsBook, Academic Press, 2001
